Mercury and Saturn conjunction in 4th house may cause a lack of peace in his mind. His mind may be full of fluids of thoughts. He may be suffering from mental stress. Native may be a negative thinker. He may be suffering from depression.
Mercury and Jupiter conjunction in the 10th house has full aspects on the house of comfort (4th house). So, native has good materialistic comfort and materialistic happiness. He will accumulate comfort with his own self efforts. Such natives will get parental property. We can say that his father has good commercial property.